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Histopathologicaltudies on the Effects of the Ethanolic Extract of the fruits of Garcinia kola on Selected Organs of the Dog International Journal of Morphology
Nottidge,H. O; Omobowale,T. O; Taiwo,V. O; Omotoso,M. A.
The ethanolic extract of Garcinia kola was administered to dogs to investígate the possible effects on selected organs of the dog. Two doses of the extract (500mg/Kg and lOOOmg/Kg) were daily administered to the test animals for a period of 6 weeks. A dose related response was observed in the severity of histopathological changes observed in the testes, liver, kidney and small intestine of animals in the test groups. Despite the reported potentially beneficial effects of Garcinia kola, its use as a medicinal plant should be with great caution.
Tipo: Journal article Palavras-chave: Garcinia kola; Dog; Histopathological effects.
Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000400044
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Sublethal and histopathological effects of trace levels of tributyltin fluoride on adult oysters Crassostrea gigas ArchiMer
Chagot, Dominique; Alzieu, Claude; Sanjuan, Jane; Grizel, Henri.
Shell malformations and histological effects of environmental concentrations of TBTF (2, 13.1 and 64.8 ng/!) were assessed on adult oysters Crassostrea gigas during a I-month experiment, incIuding both an exposure and a depuration phase. The results showed that the digestive gland is the primary target organ. Recoverable modifications were observed at the lowest concentration. Limited necrosis was observed at the highest concentration and a longer exposure could have led to extensive and irreversible tissue lesions. Shell malformations (chambering) were observed during the depuration phase. Finally the authors suggest that safe TBT levels in mariculture waters should be lower than 2 ng/l.
Tipo: Text Palavras-chave: Histopathological effects; Crassostrea gigas; Tributyltin; Effets histopathologiques; Crassostrea gigas; Tributylétain.
Ano: 1990 URL: http://archimer.ifremer.fr/doc/1990/publication-2754.pdf
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